Estriol CAS 50-27-1

Menopausal symptom management:

Treats vaginal dryness, itching, and atrophy (atrophic vaginitis) associated with low estrogen levels in postmenopausal women, often via topical creams or pessaries.

Alleviates mild to moderate menopausal symptoms (e.g., urinary incontinence, dyspareunia) with lower systemic estrogenic effects compared to other estrogens.

Hormone replacement therapy (HRT):

Used in combination with other estrogens (e.g., estradiol) or progestins for personalized HRT, particularly to reduce risks of endometrial hyperplasia in estrogen-sensitive tissues.

Reproductive health:

May be used in assisted reproductive technologies (ART) to support endometrial preparation for embryo implantation.

Historically studied for preventing preterm labor (though evidence is limited and use varies by region).

Topical applications:

Targeted treatment for urogenital atrophy, improving mucosal health and reducing recurrent urinary tract infections in postmenopausal women.

Temperature: Store at room temperature (20–25°C, 68–77°F), with short-term storage acceptable between 15–30°C (59–86°F).

Light and moisture: Keep in a tightly sealed, light-resistant container (e.g., amber glass or opaque packaging) in a dry place, away from direct sunlight, humidity, and heat.

Form-specific care:

For topical creams/gels/pessaries: Ensure the container is sealed after use to prevent contamination and moisture ingress.

For oral formulations (if available): Protect from humidity; avoid storing in bathroom cabinets.

Avoid: Freezing (unless specified by the manufacturer) and prolonged exposure to extreme temperatures or light.

Safety: Keep out of reach of children and pets; do not use after the expiration date.

Shelf life: Typically 2–3 years when stored under recommended conditions (always check the expiration date on the packaging).

Degradation risks:

Heat, light, and moisture can accelerate oxidation or decomposition, reducing potency and potentially forming inactive byproducts.

In solutions or creams, microbial contamination may occur if the container is not properly sealed, especially for multi-use products.

Discard if:

The medication shows signs of discoloration (e.g., unexpected yellowing or darkening), separation (in liquids), or an unusual odor.

The packaging is damaged, or the expiration date has passed.

Company Profile

ZHONGDA (ZHENGZHOU) INTERNATIONAL EXP.&IMP.CO.,LTD. Is a subsidiary of HENAN KANGYUAN FLAVOR GROUP CO.,LTD.

 

ZhongDa operates monomeric frag rances, synthetic fragrances, chemical raw materials, pharmaceutical and dye intermediates,agricultural and sideline products, metal materials and food flav ors etc..
It is also responsible for the procurement ( of various raw materials, instruments and equipments which are required for the production, engineering,re research and development of subsidiaries of Kangyuan group company. Relying on strong financial support, professional sales network, and high-quality product services, ZhongDa has become the partner of dom nestic and foreign manufacturers and professional customers, and it is a foreign trade-oriented enterpl rise with considerable strength in the spice industry.

ZHONGDA (ZHENGZHOU) INTERNATIONAL EXP.&IMP.CO.,LTD. was established in 2007, with a group of professional business trade, product research and development team.

 

It has rich experience in foreign trade, good domestic and international business reputation, and extensive sales channel advantages. Through the joint efforts, ZhongDa has achieved outstanding results. Our products sell well all over the country and are exp( orted to Southeast Asia, Middle East, America, Europe and other countries and regions. And enjoy high re eputation from domestic and foreign customers.
ZhongDa adheres to the tenet of"Quality first, service firs st". We sincerely hope to establish good coope rative relationship with more companies and strive to mer et the different requirements of customers. We hope that ZhongDa products will help you succeed in your pr oducts. We hope that our products will develop together in big market and create brilliant future. We sincer rely welcome customers to visit, guide and call us!

Advantages

 

1). More than 30 years of production experience and more than 10 years of export sales experience.
2). Our products have Kosher, ISO and Halal certificate.
3). Small batch shipment and sub-packaging is available.
4). Provide COA, MSDS, Health Certificate and Origin Certificate.
5). Quality first, service best.

 

FAQ

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