Product Parameters

| Item | Specification |
| Density | 1.17 |
| Melting point | 173°C |
| Boiling point | 445.9°Cat760mmHg |
| Refractive index | 1.599 |
| Flash point | 209.6°C |
| Vapor pressure | 0.0±1.1 mmHg at 25°C |
| PSA | 40.46000 |
| logP | 3.60920 |
| Appearance | White to Off-White Crystalline Powder |
Application
1). Hormone replacement therapy (HRT):
Treats menopausal symptoms (e.g., hot flashes, vaginal dryness, mood changes) and reduces the risk of osteoporosis in postmenopausal women.
Used to manage estrogen deficiency due to ovarian failure, surgical menopause, or genetic conditions (e.g., Turner syndrome).
2). Contraception:
Part of combined oral contraceptives to prevent pregnancy by inhibiting ovulation (often in combination with progestins).
3). Gender-affirming therapy:
Administered in transgender women to induce feminizing hormonal changes (e.g., breast development, fat redistribution) as part of gender-affirming care.
4). Hormonal regulation:
Treats irregular menstrual cycles, primary ovarian insufficiency, or atrophic vaginitis by restoring estrogen levels.
5). Cancer therapy (off-label):
Used palliatively in hormone-responsive cancers (e.g., breast cancer in postmenopausal women, prostate cancer) to modulate estrogen receptor activity.
6). Topical and transdermal applications:
Applied via creams, patches, or gels to target local estrogen deficiency (e.g., vaginal atrophy) with systemic effects minimized.
Storage
1). Temperature: Store at room temperature (20–25°C, 68–77°F), with short-term storage acceptable between 15–30°C (59–86°F).
2). Light and moisture: Keep in a tightly sealed, light-resistant container (e.g., amber glass vial or opaque package) in a dry place, away from direct sunlight and humidity.
3). Form-specific considerations:
For oral tablets/capsules: Protect from moisture; do not store in bathrooms or humid environments.
For injectable solutions or topical products: Follow manufacturer guidelines (e.g., some transdermal patches may require storage below 25°C).
4). Avoid: Freezing (unless specified), excessive heat, or prolonged exposure to light.
5). Safety: Keep out of reach of children and pets; discard unused portions after the expiration date.
Stability
1). Shelf life: Typically 2–3 years when stored under recommended conditions (always check the expiration date on the packaging).
2). Degradation risks:
Light, heat, and humidity can accelerate decomposition, reducing efficacy and potentially forming harmful byproducts.
Oxidation or isomerization may occur with improper storage, altering the chemical structure of β-estradiol.
3). Discard if:
The medication shows signs of discoloration (e.g., yellowing beyond the natural color), precipitation (in liquids), or an unusual odor.
The packaging is damaged, or the expiration date has passed.
Packaging
Packaging
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Company Profile
ZHONGDA (ZHENGZHOU) INTERNATIONAL EXP.&IMP.CO.,LTD. Is a subsidiary of HENAN KANGYUAN FLAVOR GROUP CO.,LTD.
ZhongDa operates monomeric frag rances, synthetic fragrances, chemical raw materials, pharmaceutical and dye intermediates,agricultural and sideline products, metal materials and food flav ors etc..
It is also responsible for the procurement ( of various raw materials, instruments and equipments which are required for the production, engineering,re research and development of subsidiaries of Kangyuan group company. Relying on strong financial support, professional sales network, and high-quality product services, ZhongDa has become the partner of dom nestic and foreign manufacturers and professional customers, and it is a foreign trade-oriented enterpl rise with considerable strength in the spice industry.


ZHONGDA (ZHENGZHOU) INTERNATIONAL EXP.&IMP.CO.,LTD. was established in 2007, with a group of professional business trade, product research and development team.
It has rich experience in foreign trade, good domestic and international business reputation, and extensive sales channel advantages. Through the joint efforts, ZhongDa has achieved outstanding results. Our products sell well all over the country and are exp( orted to Southeast Asia, Middle East, America, Europe and other countries and regions. And enjoy high re eputation from domestic and foreign customers.
ZhongDa adheres to the tenet of"Quality first, service firs st". We sincerely hope to establish good coope rative relationship with more companies and strive to mer et the different requirements of customers. We hope that ZhongDa products will help you succeed in your pr oducts. We hope that our products will develop together in big market and create brilliant future. We sincer rely welcome customers to visit, guide and call us!
Advantages
1). More than 30 years of production experience and more than 10 years of export sales experience.
2). Our products have Kosher, ISO and Halal certificate.
3). Small batch shipment and sub-packaging is available.
4). Provide COA, MSDS, Health Certificate and Origin Certificate.
5). Quality first, service best.

FAQ
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