Estradiol Benzoate CAS 50-50-0

Hormone Replacement Therapy (HRT):

Used in menopausal women to relieve symptoms of estrogen deficiency (e.g., hot flashes, vaginal dryness, atrophic vaginitis) and prevent conditions like osteoporosis and urogenital atrophy.

Prescribed for estrogen replacement in transgender women as part of gender-affirming hormone therapy to promote feminizing effects (e.g., breast development, adipose tissue redistribution).

Treatment of Hormone-Dependent Disorders:

Adjunctive palliative therapy for advanced prostate cancer in men, suppressing androgen production via negative feedback on the hypothalamic-pituitary-gonadal axis.

May be used in managing certain gynecological conditions (e.g., functional uterine bleeding, primary ovarian failure) when estrogen supplementation is indicated.

Store at room temperature (20–25°C, 68–77°F); short-term storage up to 30°C (86°F) is generally acceptable unless specified otherwise by the manufacturer.

Keep in a tightly sealed, light-resistant container to protect from moisture, oxygen, and direct light (photodegradation and oxidation are potential risks).

Store in a cool, dry place away from heat sources (e.g., avoid exposure to sunlight or proximity to heaters).

Ensure proper containment to prevent access by children and pets.

Chemical Stability:

Under recommended storage conditions, Estradiol Benzoate is stable when protected from light, moisture, and extreme temperatures.

Degradation primarily occurs through hydrolysis of the benzoate ester bond or oxidation, which can be accelerated by prolonged exposure to humidity, heat, or light, compromising potency and purity.

Shelf Life:

Unopened shelf life: Typically 2–3 years when stored in the original container under optimal conditions (always check the manufacturer's label for specific expiration dates).

Injectable formulations: If dissolved in oil (common for intramuscular use), the stability in the sealed vial remains intact until the expiration date. Once a solution is prepared or a vial is opened, follow clinical guidelines; some reconstituted solutions may require refrigeration (2–8°C) and use within 24–48 hours to maintain sterility and efficacy.

Discard products that show signs of degradation (e.g., discoloration, precipitate formation, unusual odor) or those past their expiration date.

Company Profile

ZHONGDA (ZHENGZHOU) INTERNATIONAL EXP.&IMP.CO.,LTD. Is a subsidiary of HENAN KANGYUAN FLAVOR GROUP CO.,LTD.

 

ZhongDa operates monomeric frag rances, synthetic fragrances, chemical raw materials, pharmaceutical and dye intermediates,agricultural and sideline products, metal materials and food flav ors etc..
It is also responsible for the procurement ( of various raw materials, instruments and equipments which are required for the production, engineering,re research and development of subsidiaries of Kangyuan group company. Relying on strong financial support, professional sales network, and high-quality product services, ZhongDa has become the partner of dom nestic and foreign manufacturers and professional customers, and it is a foreign trade-oriented enterpl rise with considerable strength in the spice industry.

ZHONGDA (ZHENGZHOU) INTERNATIONAL EXP.&IMP.CO.,LTD. was established in 2007, with a group of professional business trade, product research and development team.

 

It has rich experience in foreign trade, good domestic and international business reputation, and extensive sales channel advantages. Through the joint efforts, ZhongDa has achieved outstanding results. Our products sell well all over the country and are exp( orted to Southeast Asia, Middle East, America, Europe and other countries and regions. And enjoy high re eputation from domestic and foreign customers.
ZhongDa adheres to the tenet of"Quality first, service firs st". We sincerely hope to establish good coope rative relationship with more companies and strive to mer et the different requirements of customers. We hope that ZhongDa products will help you succeed in your pr oducts. We hope that our products will develop together in big market and create brilliant future. We sincer rely welcome customers to visit, guide and call us!

Advantages

 

1). More than 30 years of production experience and more than 10 years of export sales experience.
2). Our products have Kosher, ISO and Halal certificate.
3). Small batch shipment and sub-packaging is available.
4). Provide COA, MSDS, Health Certificate and Origin Certificate.
5). Quality first, service best.

 

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