Hey there! As a supplier of N-Butanol, I often get asked about all sorts of technical details regarding this chemical. One question that pops up quite frequently is, "What is the LD50 value of N-Butanol?" Well, let's dive right into it and break it down in a way that's easy to understand.
First off, let's explain what LD50 means. LD50 stands for "Lethal Dose 50%." It's a measure used in toxicology to determine the amount of a substance that is required to kill 50% of a test population (usually animals like rats or mice) when administered in a specific way, like through ingestion, inhalation, or skin contact. It's expressed in milligrams of the substance per kilogram of the test subject's body weight (mg/kg).
Now, for N-Butanol, the LD50 values can vary depending on the route of exposure. For oral ingestion in rats, the LD50 is approximately 790 mg/kg. This means that if you were to give a group of rats a dose of N-Butanol at this level, about half of them would die as a result. In terms of inhalation, the LC50 (Lethal Concentration 50%, which is similar to LD50 but for inhaled substances) for rats over a 4 - hour exposure period is around 4700 ppm (parts per million).
When it comes to skin contact, the LD50 for rabbits is about 2420 mg/kg. These values give us an idea of the relative toxicity of N-Butanol. It's not the most toxic substance out there, but it's still something that needs to be handled with care.
As a supplier, I always make sure to provide clear safety information about N-Butanol to my customers. We know that it's used in a variety of industries, from the production of plastics and rubber to the formulation of solvents and coatings. And because of its wide range of applications, it's crucial that everyone using it understands the potential risks.


N-Butanol has some pretty interesting properties. It's a clear, colorless liquid with a characteristic alcoholic odor. It's miscible with many organic solvents, which makes it a popular choice in the chemical industry. But those same properties also mean that it can be absorbed by the body through different routes, which is why the LD50 values are so important.
If you're working with N-Butanol, you need to follow proper safety procedures. Wear appropriate protective clothing, like gloves and goggles, to prevent skin and eye contact. Make sure you're working in a well - ventilated area to avoid inhaling the vapors. And of course, always store it in a cool, dry place away from sources of ignition, as it's flammable.
Now, besides N-Butanol, we also supply other high - quality chemicals. For example, we have High Quality 99% 1-Hexanol CAS 111-27-3. This is another useful alcohol that's used in the fragrance and flavor industry, as well as in the production of plasticizers. It has its own set of safety data, but like N-Butanol, we ensure that all our customers are well - informed about how to handle it safely.
We also offer 99% Propylene Glycol CAS 57-55-6. Propylene glycol is widely used in the food, pharmaceutical, and cosmetic industries. It's considered relatively safe, but still, we provide detailed safety information to our customers.
And then there's Manufacturer Supply 99% 2-Methyl-1-propanol CAS 78-83-1. This chemical is used in the production of solvents and coatings, similar to N-Butanol. We make sure that all our products meet the highest quality standards and that we're always there to support our customers with any technical questions they might have.
So, if you're in the market for N-Butanol or any of our other products, don't hesitate to reach out. Whether you're a small - scale manufacturer or a large - scale industrial user, we can provide you with the right quantity and quality of chemicals you need. We're committed to ensuring that you have a smooth and safe experience when working with our products.
In conclusion, understanding the LD50 value of N-Butanol is essential for anyone working with this chemical. It helps us gauge the potential risks and take the necessary precautions. And as a supplier, we're here to make sure that you have all the information you need to use our products safely and effectively. If you have any more questions about N-Butanol or any of our other chemicals, feel free to contact us. We're always happy to have a chat and help you out.
References:
- "The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals." Merck & Co., Inc.
- "Handbook of Toxicology of Chemical Warfare Agents." Edited by Salem, Harry, et al.
